De La Torre-Ubieta Research Lab

  • Confocal microscopy of a 750um coronal section of a Thy1-GFP mouse brain that was rendered optically transparent.
    The de la Torre-Ubieta Lab

Our Research

Our laboratory began operations in 2018 within the UCLA Department of Psychiatry and Biobehavioral Sciences and the Intellectulal and Developmental Disabilities Research Center (IDDRC). We use multidisciplinary approaches to study the gene expression patterns, gene regulatory mechanisms and histogenetic processes of the developing human brain, with emphasis in the neocortex. Our long-term goal is to translate these findings into practical therapeutics for neuropsychiatric disease.

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News

  • New study uncovers RNA editing during neurogenesis. Now in AJHG.
  • Our trainees and their mentors receive recognition at multiple events. See the News section.
  • New study uncovering the gene-isoform diversity in the developing neocortex now in Science.
  • Our developing human brain single-cell RNAseq study is now available in Neuron. 
  • Our Cell paper has been highlighted in Cell and Nature Reviews Neuroscience.